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Below resting disorders nearly all of NE produced in sympathetic nerves is metabolized prior to entry of the transmitter into the interstitial fluid or plasma.The final results introduced listed here clearly show that, while in the CNS of mice, the increased spillover of catecholamines due to deficiency of α2A- or α2C-adrenoceptors is accompanied
The action of catecholamines introduced for the synapse is terminated by diffusion and reuptake into presynaptic nerve terminalsMeasurements of 3H-labeled and endogenous NE and DHPG help estimation of prices of vesicular leakage, intraneuronal deamination of NE, and also the proportion of unveiled NE that undergoes reuptake into the nerve terminals
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